Full spectrum anabolic - AndroBulk activates all muscle building genes known to man - Androgenic, estrogenic and progestogenic action comes together for the manufacture of muscle ... learn more
Size without compromise - AndroBulk a pure size builder -- but its gentle and forgiving -- with virtually zero hair loss, acne, irritability or prostate swelling... learn more
Vessel growth - Rapid activation of angiopoietin-1 increases developement of blood vessels in muscle tissue, supporting improved circulation and accelerated muscle growth... learn more
Pain free joints - The squat rack, the football field, or the overhead keg press -- stiff achy joints can slow you down. AndroBulk blocks inflammation at the joint, allowing you to lift hard and heavy ... learn more
Comparison
AndroBulk is safer and smarter than other forms of androgens ... learn more
Injectable Steroids
Mild suppression
Maintains normal testicular function and fertility (LH & FSH). Enables quick and complete recovery after cycling.
Severe suppression
Increased risk for testicular shrinkage, prolonged recovery, reduced fertility and erectile dysfunction.
Natural 24hr rhythm
Maintains healthy cholesterol and blood values
Chronic elevation of androgens
Increases risk for heart attack, stroke and shortness of breath
Chris F. Gained 14lbs of LBM No change in body fat 25% increase in strength
Oral Delivery
We are achieving up to 98% absorption by taking advantage of the "fat uptake" system in the intestines - No needles, no creams, no liver stress
Forget multiple doses. AndroBulk keeps blood levels elevated with just ONE dose per day. Introducing Liqua-Vade 24hr
Technical Science & Research
For Healthcare & Research Professionals
Get in-depth technical information on the science and research behind AndroBulk. Recommended for heathcare and research professionals. Download White Papers
Chris F. Gained 14lbs of LBM No change in body fat 25% increase in strength
1. Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities. Attardi BJ, et al J Steroid Biochem Mol Biol. 2010 Feb 15;118(3):151-61. Epub 2009 Nov 24.
2. Nandrolone, a 19-nortestosterone, enhances insulin-independent glucose uptake in normal men. Hobbs CJ, et al. J Clin Endocrinol Metab. 1996 Apr;81(4):1582-5.
3. Progestins can mimic, inhibit and potentiate the actions of androgens. Bardin CW, et al. Pharmacol Ther. 1983;23(3):443-59.
4. Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity. Mauvais-Jarvis F. Trends Endocrinol Metab. 2011 Jan;22(1):24-33. Epub 2010 Nov 5.
5. Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different pathways. Svensson J, et al. J Mol Endocrinol. 2010 Jul;45(1):45-57. Epub 2010 Apr 30.
6. Estrogen production and action. Nelson LR, et al. J Am Acad Dermatol. 2001 Sep;45(3 Suppl):S116-24.
7. In vivo MRI evaluation of anabolic steroid precursor growth effects in a guinea pig model. Tang H, et al Steroids. 2009 Aug;74(8):684-93. Epub 2009 Mar 20.
8. Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. Babischkin JS, et al. Endocrine. 2009 Feb;35(1):81-8. Epub 2008 Nov 19.
9. The correlations between estradiol, estrone, estriol, progesterone, and sex hormone-binding globulin and anterior cruciate ligament stiffness in healthy, active females. Romani W, et al. J Womens Health (Larchmt). 2003 Apr;12(3):287-98.
10. A gender gap in autoimmunity. Whitacre CC, et al. Science. 1999 Feb 26;283(5406):1277-8.
11. Body composition and anthropometry in bodybuilders: regional changes due to nandrolone decanoate administration. Hartgens F, et al. Int J Sports Med. 2001 Apr;22(3):235-41.
12. The role of non-aromatizable testosterone metabolite in metabolic pathways. Dušková M, et al. Physiol Res. 2011 May 10;60(2):253-61. Epub 2010 Nov 29.
13. Of mice and men: the many guises of estrogens. Simpson ER, et al. Ernst Schering Found Symp Proc. 2006;(1):45-67.
14. Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. Babischkin JS, et al. Endocrine. 2009 Feb;35(1):81-8. Epub 2008 Nov 19.
15. Endogenous estrogens influence endothelial function in young men. Lew R, et al. Circ Res. 2003 Nov 28;93(11):1127-33. Epub 2003 Oct 30.
16. Long term perturbation of endocrine parameters and cholesterol metabolism after discontinued abuse of anabolic androgenic steroids. Gårevik N, et al. J Steroid Biochem Mol Biol. 2011 Aug 22. [Epub ahead of print]
17. The relationship between pubertal gynecomastia, prostate specific antigen, free androgen index, SHBG and sex steroids. Kilic M, et al. J Pediatr Endocrinol Metab. 2011;24(1-2):61-7.
18. [Persistant pubertal gynecomastia. Biological study (author's transl)]. [Article in French] Sultan C, et al. Sem Hop. 1980 Dec 8-15;56(45-46):1923-30.
19. Gynecomastia: effect of prolonged treatment with dihydrotestosterone by the percutaneous route. Kuhn J et al. Presse Med 12;21-25. (1983)
20. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. Eberle AJ, et al J Pediatr. 1986 Jul;109(1):144-9.
21. An antiestrogenic action of androgens in human breast cancer cells. MacIndoe JH, et al. J Clin Endocrinol Metab. 1981 Oct;53(4):836-42.
22. Evaluation of androgen antagonism of estrogen effect by dihydrotestosterone. Hung TT, et al. J Steroid Biochem. 1983 Oct;19(4):1513-20.
23. Very small embryonic-like stem cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies. Zuba-Surma EK, et al. Cytometry A. 2008 Dec;73A(12):1116-27.
24. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Singh R, et al. Endocrinology. 2003 Nov;144(11):5081-8. Epub 2003 Jul 24.
25. Effects of anabolic steroids on the muscle cells of strength-trained athletes. Kadi F, et al. Med Sci Sports Exerc 31:1528–1534. (1999)
26. Testosterone-induced increase in muscle size in healthy young men is associated with muscle ber hypertrophy. Sinha-Hikim I, et al. Am J Physiol Endocrinol Metab 283:E154–E164 (2002)
27. Myonuclei acquired by overload exercise precede hypertrophyand are not lost on detraining. Bruusgaard JC. et al. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15111-6. Epub 2010 Aug 16.
28. Strength Training and Anabolic Steroids Anders Eriksson, et al. University Medical Dissertations (2006)
29-38. Ignore
39. Testosterone dose-response relationships in healthy young men. Bhasin S, et al. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81.
40. Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men. Woodhouse LJ, et al. J Clin Endocrinol Metab. 2004 Feb;89(2):718-26.
41. Testosterone Threshold Levels and Lean Tissue Mass Targets Needed to Enhance Skeletal Muscle Strength and Function: The HORMA Trial. Sattler, F et al. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):122-9.
42. Conversion of androsterone ester to dihydrotestosterone (DHT) -- with 10 hour pharmacokinetics Draws performed by AnyLabTestNow, 714 SW Washington St, Portland, OR 97205 , July 2011. Analysis performed by S.E.D. Medical Laboratories. (Contact Primordial Performance for full report)
43. In vivo conversion of dehydroisoandrosterone to plasma androstenedione and testosterone in man. Horton R, et al. J Clin Endocrinol Metab. 1967 Jan;27(1):79-88.
44. In vitro metabolism of androgens in whole human blood. Blaquier et al. Acta Endocrinol (Copenh). 1967 Aug;55(4):697-704. No abstract available.
45. METABOLISM OF ANDROST-4-ENE-3,17-DIONE-4-14C BY RABBIT SKELETAL MUSCLE SUPERNATANT FRACTION. ISOLATION OF 3BETA-HYDROXYANDROST-4-EN-17-ONE-14C AND TESTOSTERONE-14C. THOMAS et al. J Biol Chem. 1964 Mar;239:766-72. No abstract available
46. Direct agonist/antagonist functions of dehydroepiandrosterone. Chen et al. Endocrinology. 2005 Nov; 146(11):4568-76. Epub 2005 Jun 30
47. Serum androgen bioactivity during 5alpha-dihydrotestosterone treatment in elderly men. Raivio et al. J Androl. 2002 Nov-Dec;23(6):919-21.
48. In vitro bioassays for androgens and their diagnostic applications. Roy et al. Hum Reprod Update. 2008 Jan-Feb;14(1):73-82. Epub 2007 Dec 4.
49. Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay. Roy et al. J Steroid Biochem Mol Biol. 2006 Sep; 101(1):68-77. Epub 2006 Aug 8.
50. Circulating bioactive androgens in midlife women. Chen et al. J Clin Endocrinol Metab. 2006 Nov;91(11):4387-94. Epub 2006 Aug 29.
51. Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol. Chen Fet al. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):247-57.
52. Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men. Jasuja R, et al. J Clin Endocrinol Metab. 2005 Feb;90(2):855-63. Epub 2004 Nov 2.
53. In vivo MRI evaluation of anabolic steroid precursor growth effects in a guinea pig model. Tang H, et al Steroids. 2009 Aug;74(8):684-93. Epub 2009 Mar 20.
One Man with the Power of Three
We harnessed the power of androgens, estrogens and progestins with Super-4-DHEA and Super-19-DHEA -- The result is one heavy hitter. (1-8)
Super-4-DHEA has balanced androgenic, anabolic and estrogenic activity -- making it a potent muscle building androgen that's pretty damn close to actual testosterone. (46-51) It converts very well to the potent anabolic androstenediol, which then converts to testosterone -
Super-19-DHEA differs by having a stronger anabolic activity, and weaker androgenic activity. (1) It also has some progestational activity, which helps reduce inflammation in the joints and increase the anabolic effect of androgens. (3,9,10) Its converts well the super-cool anabolic known as bolandiol, which then converts to 19-nortestosterone -
AndroMass vs. AndroBulk
A popular question we've had since the announcement of AndroBulk is --
"Whats the difference between AndroMass and AndroBulk??"
So lets just get right down to the science of it...
Incredible Hulk = AndroMass
The Thing = AndroBulk
Round 1 - The Hulk is generally more aggressive, and has the potential for greater strength because of his ever building irritation towards opposition. His out-of-control rage gives him great power. The Thing is not so easily irritated, and thus is not quite as powerful as the Hulk.
AndroMass wins for more strength and aggression.
Round 2 - The Thing is a bit more humble and reserved. He also deals with less side effects like prostate hypertrophy, irritability and hair loss (if he had hair) -- because of lower overall androgenic activity. (e.g. DHT) (10,19)
AndroBulk wins for less side effects.
In the end, overall size and mass gains are about the same. It comes down to deciding between maximum sheer strength vs. lower androgenic side-effects. For instance, if you’re a professional power lifter, the aggression of AndroMass will be great, but if your substitute teacher for 3rd graders, AndroBulk might be a safer choice.
Estrogen for Muscle
Yes, the "female" hormone has some pretty important muscle building activity. (4-6,13,14)
Recent research shows that estrogen regulates at least 51 muscle building genes, while androgens regulate 187 genes. (5) Therefore, if you want to activate all 225 genes* for muscle building you need maintain moderate to high levels of estrogen. Estrogen increases IGF-1 release, blood vessel growth, and nutrient uptake in muscles. (4-6,13,14)
Plus, estrogen is important for maintaining blood vessel dilation and increased blood flow for good solid erections. (14,15)
* Androgens and estrogens have 13 overlaping genes
Oh My Achy Joints!
Ever notice how arthritic women have little-to-no joint pain when they are pregnant?
This is the power of estrogen and progesterone -- They have a synergistic effect in reducing joint stiffness by exerting an anti-inflammatory action upon the joint tissue. (9,10) Remember, Super-19-DHEA has potent progesterone-like effects. (1)
These hormones work by activating the T-helper 2 (TH2) response, which suppresses pro-inflammatory TH1, and allows the joints to be more mobile, even under heavy load. (9,10)
If you are a heavy weight lifter -- you probably realize the benefit here.
Joint discomfort can put mass gains to halt. Nobody wants to squat 400lbs and drop ass to grass with stiff, achy joints. All of our AndroBulk testers noticed increased joint comfort -- which seemed to kick in within the first couple weeks of the cycle.
Growing Breasts on AndroBulk
With all this talk of "estrogen" and "progesterone" you are probably worried about growing breasts or sore swollen nipples -- since this can be a common side-effect with many steroids. (16)
First of all, all men have estrogen in their body, and getting gyno has almost nothing to do with high estrogen. (17-22) In fact, research shows that the most important indicator for gyno is the ratio of androgens to estrogens. (17-22) For example, if you have low estrogen, but even lower androgens, you are at a higher risk for gyno than someone who has high estrogens, with even higher androgens. Its all about the ratio.
Considering this, we included Super-4-DHEA with Super-19-DHEA at a percise 3 to 1 ratio to balance the androgenic and estrogenic activity for the lowest risk of gyno -- while still allowing AndroBulk to have minimal androgenic side effects like hair loss and acne.
This was confirmed to be effective, since non of our three AndroBulk testers had even the slightest gyno symptoms over 4 and 8 week cycles.
NOTE: If you already have gyno, and are extremely sensitive to irritation, then you may be safer with AndroMass -- due to its stronger androgenic action.
Embryonic Muscle Cells
Many years ago, you were given a gift.
While you where growing your mother’s uterus, you where gifted with "very small embryonic-like stem cells" (VSELs) -- deposited into your muscle tissue. (among other organs) (23)
Up until several years ago, scientists didn't even know these existed -- so this was a pretty big deal when this was discovered. VSELs are basically small cells with an undetermined lineage -- meaning they can convert into just about anything -- such as new muscle cells or fat cells.
Through most of your adult life, these little cells sit in a dormant state -- that is -- until something significant enough activates them to turn into something meaningful.
So how do you activate them to turn into muscle?
You guessed it -- Androgens. (24)
Bigger Veins for Bigger Muscles
The first thing your body must do to support new muscle mass, is to bring the constant supply of protein, amino acids and ionic fluid.
The 19-norandrogen in AndroBulk initiates several genes that activate angiogenesis -- The development of new microvascular in muscle. (5,8)
This is another great benefit from the estrogenic action of AndroBulk -- something that non-estrogenic androgens don’t really help with. (5)
Multiplying - Feeding - Building
Virtually every aspect of muscle growth is initiated by AndroBulk
It leaves nothing behind and makes sure that all aspects are moving towards bigger, stronger, more explosive muscles.
Here is what you get -
1. New muscle cells - Differentiation of stem cells into muscle cells
2. New nuclei - Increased protein synthesis ability
3. More nutrient delivery - More blood vessels / more blood cells
4. More nutrients retained - Increased utilization of amino-acids for new tissue growth
As you have already learned, some of the effects such as the increased nuclei, myoblasts, and blood vessels may stick around for quite some time -- if not for the rest of your life. (25-28)
Smart Investment
We understand that AndroSeries products cost more than your average fitness supplement -- but we are here to provide the best androgen supplements in the world, and that’s our #1 goal.
Consider the things you DON’T need by using safer, and less suppressive androgens like the AndroSeries -
Liver, kidney, or blood pressure protection
Little blue pills to keep "things working"
Harsh "research grade" PCT drugs
Needles & sterilization
As with any androgen, you will still need a PCT, but recovery will be quick and easy with our safe and natural PCT products.
Not all effects from AndroSeries products will last forever, but some may, and with a little effort in maintaining a solid diet and training program you can keep a large portion of your gains.
Invest in your body, and invest in future innovation.
We appreciate the support.
Androgenically, Eric Potratz
Primordial Founder & President
References:
See references tab.
The AndroStat
Find your perfect dose
Men with low androgens will naturally get the most significant and rapid effects from androgen supplementation -- simply because they are more sensitive to the effects of androgens. The effects may become apparent within a few days, and even more apparent as time goes on. (figure 1)
On the other hand, men with higher androgen levels may not feel the benefits of androgens as dramatically -- simply because they are accustomed to the effects of high androgens already. Many of the immediate effects, like increased sex drive or aggression may not be noticeable to a man with high androgen levels -- as these aspects may already be optimized. In this case, noticeable change may not be realized until several weeks into a cycle, as new muscle tissue begins to take shape. (figure 1)
Thus, men with higher androgen levels will need a higher dose of androgens than men with low androgens, in order to surpass the threshold required for new lean mass and strength.
Considering this, we designed the AndroStat to determine your androgen levels (e.g. testosterone) with nearly 85-100% accuracy.
Give it a shot. It only takes about 30 seconds to complete.
Once the questions are answered it will help you determine an appropriate dose.
---------
AndroBulk Power Rating
1 Pill = ↑ 450ng/dL Testosterone Equivalent
Research shows that androgen levels (e.g. testosterone) must increase by ~1000ng/dl to add 3.3lbs of new lean body mass, and to enhance strength by 30%. (without training or diet intervention) (39-41)
In-house research, in addition to outside studies, show that a daily dose of 6 AndroBulk softgels increases androgens enough to match the overall bio-activity of a 2700ng/dL testosterone level. (42-51)
Therefore, if your testosterone level is currently 700ng/dL, then 6 softgels of AndroBulk will provide enough "testosterone-activity" to surpass the threshold 2x and increase lean body mass by 6.6lbs over 8 weeks -- if you change no factors at all.
Results from our in-house subjects shows that additional lean mass and strength can be obtained by following an appropriate diet and training program.
---------
Testosterone is NOT the only Androgen!
Testosterone has long been the "gold standard" for male androgens. It’s the first hormone usually considered for testosterone replacement therapy (TRT), and it’s easily the most researched androgen over the past 80 years.
But new research is showing its not the only muscle building androgen.
For example, several human and animals studies show that androstenedione and androstenediol actually have some fairly potent muscle building effects (52,53). Most interesting is that these studies showed that testosterone was not the active androgen causing these effects. The androgen supplementation caused only a moderate increases in testosterone -- yet the animals and humans were gaining muscle and losing body fat as if they had super-high testosterone levels. (52,53)
The explanation?
The androstenedione and androstenediol where building muscle themselves, proving that other androgens besides just testosterone, can be potent muscle building agents.
This fact is also supported by test-tube studies showing that these androgens bind to the androgen receptor in muscle tissue and directly initiate muscle growth. (46-52)
However, we still compare our AndroSeries products to testosterone just for simplicities sake. To read more about the "testosterone equivalent" of AndroSeries products visit this article - Whats new with AndroSeries v3?
---------
Figure 1
---------
Need Diet and Training Suggestions?
Get Your FREE Handbook
Every AndroSeries product contains its own Ultimate Results handbook.*
The handbook Includes -
1. Diet tips - Helpful suggestions on the type of foods to eat for the best results.
2. Training tips - Workout designed for the best results depending on the product. Provides a "recommended workout" including exercises, sets and reps.
3. Dosing and cycling tips - Provides info on getting the best results, proper post cycle therapy (PCT), and how to avoid side-effects.
High stearic shea nut oil, glyceryl monolinoleate/oleate, high linoleic safflower seed oil, phospholipid complex [standardized tp 35% phosphatidylcholine], ethoxylated sorbitan monooleate,Hormone Protection Complex™(Grapefruit peel oil, naringenin and quercetin extract) and medium chain triclycerides.
*Daily Value not established
Other Ingredients:
Kosher gelatin, tocopheryl acetate, glycerin, purified water, titanium dioxide, grape spirits, FD&C Blue #1, FD&C Blue #1 Alum. Lake, and FD&C Red #40 Alum. Lake.
† May be derived from soy
Recommended Use:
As a dietary supplement take 3-6 softgels upon rising, once daily. Take with or without meals. Do not exceed 6 softgels in a 24h period.
Do not use this product longer than 8 weeks without taking 8 weeks off between each cycle. 8 week off-time must exclude all steroidal products.
This product may be stacked with other AndroSeries™ products. For stacking recommendations, scan the QR code and see AndroStat, or visit www.androseries.info/androstat. Do not exceed 12 softgels total in a 24h period.
WARNING:
This product is not recommended for women, the elderly, anyone under the age of 21 or anyone diagnosed with a serious health condition including but not limited to cancer, BPH, epilepsy, depression, diabetes, cardiovascular disease or high blood pressure. Temporary side effects of this product may include weight gain, mildly reduced fertility, irritability, and oily skin.
Warning – Drug Interaction: A full serving (6 softgels) of this product contains the equivalent drug interaction effect of ~8fl. oz (240mL) of grapefruit juice which can significantly increase absorption of certain prescription drugs causing severe side-effects from overdose. A single dose of this product may influence the absorption of drugs for up to 24 hours. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. For more information, scan the QR code, or visit www.androseries.info/druginteractions.
Warning - Contains Steroids: Using this product may result in a positive test for steroids in organizations testing for performance enhancing compounds. This includes, IOC, NCAA, WADA, NFL, MLB, and other various sports and government agencies. This does NOT include typical pre-employment drug screening.
NOTICE:
This product is not intended to diagnose, treat, cure, or prevent any disease. Shipping Not Available to: Canada, Sweden, Singapore, Germany, or Australia.
AndroBulk
Cycle Guidelines
And Recommended Stacks
8 Week
Muscle & Size
8 Week
Muscle & Size + More Power
8 Week
Muscle & Size + More Size & Power
8-14lbs in lean mass
10-15% increase in strength
Reduced joint stiffness
10-15lbs in lean mass
20-35% increase in strength
Reduced joint stiffness
12-18lbs in lean mass
20-40% increase in strength
Reduced joint stiffness
Increased aggression
Week 1
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 2
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 3
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 4
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 5
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 6
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 7
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 8
6 AndroBulk*
6 AndroBulk + 3 AndroHard*
6 AndroBulk + 3 AndroMass*
Week 9
Post Cycle Therapy (PCT)
Week 10
Week 11
Week 12
*Take dose once daily, preferably upon rising.
See the AndroStacker for more information on effects, side-effects, and androgen levels.
Full spectrum anabolic - AndroBulk activates all muscle building genes known to man - Androgenic, estrogenic and progestogenic action comes together for the manufacture of muscle ... learn more
Size without compromise - AndroBulk a pure size builder -- but its gentle and forgiving -- with virtually zero hair loss, acne, irritability or prostate swelling... learn more
Vessel growth - Rapid activation of angiopoietin-1 increases developement of blood vessels in muscle tissue, supporting improved circulation and accelerated muscle growth... learn more
Pain free joints - The squat rack, the football field, or the overhead keg press -- stiff achy joints can slow you down. AndroBulk blocks inflammation at the joint, allowing you to lift hard and heavy ... learn more
Comparison
AndroBulk is safer and smarter than other forms of androgens ... learn more
Injectable Steroids
Mild suppression
Maintains normal testicular function and fertility (LH & FSH). Enables quick and complete recovery after cycling.
Severe suppression
Increased risk for testicular shrinkage, prolonged recovery, reduced fertility and erectile dysfunction.
Natural 24hr rhythm
Maintains healthy cholesterol and blood values
Chronic elevation of androgens
Increases risk for heart attack, stroke and shortness of breath
Chris F. Gained 14lbs of LBM No change in body fat 25% increase in strength
Oral Delivery
We are achieving up to 98% absorption by taking advantage of the "fat uptake" system in the intestines - No needles, no creams, no liver stress
Forget multiple doses. AndroBulk keeps blood levels elevated with just ONE dose per day. Introducing Liqua-Vade 24hr
Technical Science & Research
For Healthcare & Research Professionals
Get in-depth technical information on the science and research behind AndroBulk. Recommended for heathcare and research professionals. Download White Papers
Chris F. Gained 14lbs of LBM No change in body fat 25% increase in strength
1. Mechanism of action of bolandiol (19-nortestosterone-3beta,17beta-diol), a unique anabolic steroid with androgenic, estrogenic, and progestational activities. Attardi BJ, et al J Steroid Biochem Mol Biol. 2010 Feb 15;118(3):151-61. Epub 2009 Nov 24.
2. Nandrolone, a 19-nortestosterone, enhances insulin-independent glucose uptake in normal men. Hobbs CJ, et al. J Clin Endocrinol Metab. 1996 Apr;81(4):1582-5.
3. Progestins can mimic, inhibit and potentiate the actions of androgens. Bardin CW, et al. Pharmacol Ther. 1983;23(3):443-59.
4. Estrogen and androgen receptors: regulators of fuel homeostasis and emerging targets for diabetes and obesity. Mauvais-Jarvis F. Trends Endocrinol Metab. 2011 Jan;22(1):24-33. Epub 2010 Nov 5.
5. Stimulation of both estrogen and androgen receptors maintains skeletal muscle mass in gonadectomized male mice but mainly via different pathways. Svensson J, et al. J Mol Endocrinol. 2010 Jul;45(1):45-57. Epub 2010 Apr 30.
6. Estrogen production and action. Nelson LR, et al. J Am Acad Dermatol. 2001 Sep;45(3 Suppl):S116-24.
7. In vivo MRI evaluation of anabolic steroid precursor growth effects in a guinea pig model. Tang H, et al Steroids. 2009 Aug;74(8):684-93. Epub 2009 Mar 20.
8. Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. Babischkin JS, et al. Endocrine. 2009 Feb;35(1):81-8. Epub 2008 Nov 19.
9. The correlations between estradiol, estrone, estriol, progesterone, and sex hormone-binding globulin and anterior cruciate ligament stiffness in healthy, active females. Romani W, et al. J Womens Health (Larchmt). 2003 Apr;12(3):287-98.
10. A gender gap in autoimmunity. Whitacre CC, et al. Science. 1999 Feb 26;283(5406):1277-8.
11. Body composition and anthropometry in bodybuilders: regional changes due to nandrolone decanoate administration. Hartgens F, et al. Int J Sports Med. 2001 Apr;22(3):235-41.
12. The role of non-aromatizable testosterone metabolite in metabolic pathways. Dušková M, et al. Physiol Res. 2011 May 10;60(2):253-61. Epub 2010 Nov 29.
13. Of mice and men: the many guises of estrogens. Simpson ER, et al. Ernst Schering Found Symp Proc. 2006;(1):45-67.
14. Estrogen stimulates the human endometrium to express a factor(s) that promotes vascular smooth muscle cell migration as an early step in microvessel remodeling. Babischkin JS, et al. Endocrine. 2009 Feb;35(1):81-8. Epub 2008 Nov 19.
15. Endogenous estrogens influence endothelial function in young men. Lew R, et al. Circ Res. 2003 Nov 28;93(11):1127-33. Epub 2003 Oct 30.
16. Long term perturbation of endocrine parameters and cholesterol metabolism after discontinued abuse of anabolic androgenic steroids. Gårevik N, et al. J Steroid Biochem Mol Biol. 2011 Aug 22. [Epub ahead of print]
17. The relationship between pubertal gynecomastia, prostate specific antigen, free androgen index, SHBG and sex steroids. Kilic M, et al. J Pediatr Endocrinol Metab. 2011;24(1-2):61-7.
18. [Persistant pubertal gynecomastia. Biological study (author's transl)]. [Article in French] Sultan C, et al. Sem Hop. 1980 Dec 8-15;56(45-46):1923-30.
19. Gynecomastia: effect of prolonged treatment with dihydrotestosterone by the percutaneous route. Kuhn J et al. Presse Med 12;21-25. (1983)
20. Treatment of persistent pubertal gynecomastia with dihydrotestosterone heptanoate. Eberle AJ, et al J Pediatr. 1986 Jul;109(1):144-9.
21. An antiestrogenic action of androgens in human breast cancer cells. MacIndoe JH, et al. J Clin Endocrinol Metab. 1981 Oct;53(4):836-42.
22. Evaluation of androgen antagonism of estrogen effect by dihydrotestosterone. Hung TT, et al. J Steroid Biochem. 1983 Oct;19(4):1513-20.
23. Very small embryonic-like stem cells are present in adult murine organs: ImageStream-based morphological analysis and distribution studies. Zuba-Surma EK, et al. Cytometry A. 2008 Dec;73A(12):1116-27.
24. Androgens stimulate myogenic differentiation and inhibit adipogenesis in C3H 10T1/2 pluripotent cells through an androgen receptor-mediated pathway. Singh R, et al. Endocrinology. 2003 Nov;144(11):5081-8. Epub 2003 Jul 24.
25. Effects of anabolic steroids on the muscle cells of strength-trained athletes. Kadi F, et al. Med Sci Sports Exerc 31:1528–1534. (1999)
26. Testosterone-induced increase in muscle size in healthy young men is associated with muscle ber hypertrophy. Sinha-Hikim I, et al. Am J Physiol Endocrinol Metab 283:E154–E164 (2002)
27. Myonuclei acquired by overload exercise precede hypertrophyand are not lost on detraining. Bruusgaard JC. et al. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15111-6. Epub 2010 Aug 16.
28. Strength Training and Anabolic Steroids Anders Eriksson, et al. University Medical Dissertations (2006)
29-38. Ignore
39. Testosterone dose-response relationships in healthy young men. Bhasin S, et al. Am J Physiol Endocrinol Metab. 2001 Dec;281(6):E1172-81.
40. Dose-dependent effects of testosterone on regional adipose tissue distribution in healthy young men. Woodhouse LJ, et al. J Clin Endocrinol Metab. 2004 Feb;89(2):718-26.
41. Testosterone Threshold Levels and Lean Tissue Mass Targets Needed to Enhance Skeletal Muscle Strength and Function: The HORMA Trial. Sattler, F et al. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):122-9.
42. Conversion of androsterone ester to dihydrotestosterone (DHT) -- with 10 hour pharmacokinetics Draws performed by AnyLabTestNow, 714 SW Washington St, Portland, OR 97205 , July 2011. Analysis performed by S.E.D. Medical Laboratories. (Contact Primordial Performance for full report)
43. In vivo conversion of dehydroisoandrosterone to plasma androstenedione and testosterone in man. Horton R, et al. J Clin Endocrinol Metab. 1967 Jan;27(1):79-88.
44. In vitro metabolism of androgens in whole human blood. Blaquier et al. Acta Endocrinol (Copenh). 1967 Aug;55(4):697-704. No abstract available.
45. METABOLISM OF ANDROST-4-ENE-3,17-DIONE-4-14C BY RABBIT SKELETAL MUSCLE SUPERNATANT FRACTION. ISOLATION OF 3BETA-HYDROXYANDROST-4-EN-17-ONE-14C AND TESTOSTERONE-14C. THOMAS et al. J Biol Chem. 1964 Mar;239:766-72. No abstract available
46. Direct agonist/antagonist functions of dehydroepiandrosterone. Chen et al. Endocrinology. 2005 Nov; 146(11):4568-76. Epub 2005 Jun 30
47. Serum androgen bioactivity during 5alpha-dihydrotestosterone treatment in elderly men. Raivio et al. J Androl. 2002 Nov-Dec;23(6):919-21.
48. In vitro bioassays for androgens and their diagnostic applications. Roy et al. Hum Reprod Update. 2008 Jan-Feb;14(1):73-82. Epub 2007 Dec 4.
49. Determination of androgen bioactivity in human serum samples using a recombinant cell based in vitro bioassay. Roy et al. J Steroid Biochem Mol Biol. 2006 Sep; 101(1):68-77. Epub 2006 Aug 8.
50. Circulating bioactive androgens in midlife women. Chen et al. J Clin Endocrinol Metab. 2006 Nov;91(11):4387-94. Epub 2006 Aug 29.
51. Partial agonist/antagonist properties of androstenedione and 4-androsten-3beta,17beta-diol. Chen Fet al. J Steroid Biochem Mol Biol. 2004 Aug;91(4-5):247-57.
52. Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men. Jasuja R, et al. J Clin Endocrinol Metab. 2005 Feb;90(2):855-63. Epub 2004 Nov 2.
53. In vivo MRI evaluation of anabolic steroid precursor growth effects in a guinea pig model. Tang H, et al Steroids. 2009 Aug;74(8):684-93. Epub 2009 Mar 20.
One Man with the Power of Three
We harnessed the power of androgens, estrogens and progestins with Super-4-DHEA and Super-19-DHEA -- The result is one heavy hitter. (1-8)
Super-4-DHEA has balanced androgenic, anabolic and estrogenic activity -- making it a potent muscle building androgen that's pretty damn close to actual testosterone. (46-51) It converts very well to the potent anabolic androstenediol, which then converts to testosterone -
Super-19-DHEA differs by having a stronger anabolic activity, and weaker androgenic activity. (1) It also has some progestational activity, which helps reduce inflammation in the joints and increase the anabolic effect of androgens. (3,9,10) Its converts well the super-cool anabolic known as bolandiol, which then converts to 19-nortestosterone -
AndroMass vs. AndroBulk
A popular question we've had since the announcement of AndroBulk is --
"Whats the difference between AndroMass and AndroBulk??"
So lets just get right down to the science of it...
Incredible Hulk = AndroMass
The Thing = AndroBulk
Round 1 - The Hulk is generally more aggressive, and has the potential for greater strength because of his ever building irritation towards opposition. His out-of-control rage gives him great power. The Thing is not so easily irritated, and thus is not quite as powerful as the Hulk.
AndroMass wins for more strength and aggression.
Round 2 - The Thing is a bit more humble and reserved. He also deals with less side effects like prostate hypertrophy, irritability and hair loss (if he had hair) -- because of lower overall androgenic activity. (e.g. DHT) (10,19)
AndroBulk wins for less side effects.
In the end, overall size and mass gains are about the same. It comes down to deciding between maximum sheer strength vs. lower androgenic side-effects. For instance, if you’re a professional power lifter, the aggression of AndroMass will be great, but if your substitute teacher for 3rd graders, AndroBulk might be a safer choice.
Estrogen for Muscle
Yes, the "female" hormone has some pretty important muscle building activity. (4-6,13,14)
Recent research shows that estrogen regulates at least 51 muscle building genes, while androgens regulate 187 genes. (5) Therefore, if you want to activate all 225 genes* for muscle building you need maintain moderate to high levels of estrogen. Estrogen increases IGF-1 release, blood vessel growth, and nutrient uptake in muscles. (4-6,13,14)
Plus, estrogen is important for maintaining blood vessel dilation and increased blood flow for good solid erections. (14,15)
* Androgens and estrogens have 13 overlaping genes
Oh My Achy Joints!
Ever notice how arthritic women have little-to-no joint pain when they are pregnant?
This is the power of estrogen and progesterone -- They have a synergistic effect in reducing joint stiffness by exerting an anti-inflammatory action upon the joint tissue. (9,10) Remember, Super-19-DHEA has potent progesterone-like effects. (1)
These hormones work by activating the T-helper 2 (TH2) response, which suppresses pro-inflammatory TH1, and allows the joints to be more mobile, even under heavy load. (9,10)
If you are a heavy weight lifter -- you probably realize the benefit here.
Joint discomfort can put mass gains to halt. Nobody wants to squat 400lbs and drop ass to grass with stiff, achy joints. All of our AndroBulk testers noticed increased joint comfort -- which seemed to kick in within the first couple weeks of the cycle.
Growing Breasts on AndroBulk
With all this talk of "estrogen" and "progesterone" you are probably worried about growing breasts or sore swollen nipples -- since this can be a common side-effect with many steroids. (16)
First of all, all men have estrogen in their body, and getting gyno has almost nothing to do with high estrogen. (17-22) In fact, research shows that the most important indicator for gyno is the ratio of androgens to estrogens. (17-22) For example, if you have low estrogen, but even lower androgens, you are at a higher risk for gyno than someone who has high estrogens, with even higher androgens. Its all about the ratio.
Considering this, we included Super-4-DHEA with Super-19-DHEA at a percise 3 to 1 ratio to balance the androgenic and estrogenic activity for the lowest risk of gyno -- while still allowing AndroBulk to have minimal androgenic side effects like hair loss and acne.
This was confirmed to be effective, since non of our three AndroBulk testers had even the slightest gyno symptoms over 4 and 8 week cycles.
NOTE: If you already have gyno, and are extremely sensitive to irritation, then you may be safer with AndroMass -- due to its stronger androgenic action.
Embryonic Muscle Cells
Many years ago, you were given a gift.
While you where growing your mother’s uterus, you where gifted with "very small embryonic-like stem cells" (VSELs) -- deposited into your muscle tissue. (among other organs) (23)
Up until several years ago, scientists didn't even know these existed -- so this was a pretty big deal when this was discovered. VSELs are basically small cells with an undetermined lineage -- meaning they can convert into just about anything -- such as new muscle cells or fat cells.
Through most of your adult life, these little cells sit in a dormant state -- that is -- until something significant enough activates them to turn into something meaningful.
So how do you activate them to turn into muscle?
You guessed it -- Androgens. (24)
Bigger Veins for Bigger Muscles
The first thing your body must do to support new muscle mass, is to bring the constant supply of protein, amino acids and ionic fluid.
The 19-norandrogen in AndroBulk initiates several genes that activate angiogenesis -- The development of new microvascular in muscle. (5,8)
This is another great benefit from the estrogenic action of AndroBulk -- something that non-estrogenic androgens don’t really help with. (5)
Multiplying - Feeding - Building
Virtually every aspect of muscle growth is initiated by AndroBulk
It leaves nothing behind and makes sure that all aspects are moving towards bigger, stronger, more explosive muscles.
Here is what you get -
1. New muscle cells - Differentiation of stem cells into muscle cells
2. New nuclei - Increased protein synthesis ability
3. More nutrient delivery - More blood vessels / more blood cells
4. More nutrients retained - Increased utilization of amino-acids for new tissue growth
As you have already learned, some of the effects such as the increased nuclei, myoblasts, and blood vessels may stick around for quite some time -- if not for the rest of your life. (25-28)
Smart Investment
We understand that AndroSeries products cost more than your average fitness supplement -- but we are here to provide the best androgen supplements in the world, and that’s our #1 goal.
Consider the things you DON’T need by using safer, and less suppressive androgens like the AndroSeries -
Liver, kidney, or blood pressure protection
Little blue pills to keep "things working"
Harsh "research grade" PCT drugs
Needles & sterilization
As with any androgen, you will still need a PCT, but recovery will be quick and easy with our safe and natural PCT products.
Not all effects from AndroSeries products will last forever, but some may, and with a little effort in maintaining a solid diet and training program you can keep a large portion of your gains.
Invest in your body, and invest in future innovation.
We appreciate the support.
Androgenically, Eric Potratz
Primordial Founder & President
References:
See references tab.
The AndroStat
Find your perfect dose
Men with low androgens will naturally get the most significant and rapid effects from androgen supplementation -- simply because they are more sensitive to the effects of androgens. The effects may become apparent within a few days, and even more apparent as time goes on. (figure 1)
On the other hand, men with higher androgen levels may not feel the benefits of androgens as dramatically -- simply because they are accustomed to the effects of high androgens already. Many of the immediate effects, like increased sex drive or aggression may not be noticeable to a man with high androgen levels -- as these aspects may already be optimized. In this case, noticeable change may not be realized until several weeks into a cycle, as new muscle tissue begins to take shape. (figure 1)
Thus, men with higher androgen levels will need a higher dose of androgens than men with low androgens, in order to surpass the threshold required for new lean mass and strength.
Considering this, we designed the AndroStat to determine your androgen levels (e.g. testosterone) with nearly 85-100% accuracy.
Give it a shot. It only takes about 30 seconds to complete.
Once the questions are answered it will help you determine an appropriate dose.
---------
AndroBulk Power Rating
1 Pill = ↑ 450ng/dL Testosterone Equivalent
Research shows that androgen levels (e.g. testosterone) must increase by ~1000ng/dl to add 3.3lbs of new lean body mass, and to enhance strength by 30%. (without training or diet intervention) (39-41)
In-house research, in addition to outside studies, show that a daily dose of 6 AndroBulk softgels increases androgens enough to match the overall bio-activity of a 2700ng/dL testosterone level. (42-51)
Therefore, if your testosterone level is currently 700ng/dL, then 6 softgels of AndroBulk will provide enough "testosterone-activity" to surpass the threshold 2x and increase lean body mass by 6.6lbs over 8 weeks -- if you change no factors at all.
Results from our in-house subjects shows that additional lean mass and strength can be obtained by following an appropriate diet and training program.
---------
Testosterone is NOT the only Androgen!
Testosterone has long been the "gold standard" for male androgens. It’s the first hormone usually considered for testosterone replacement therapy (TRT), and it’s easily the most researched androgen over the past 80 years.
But new research is showing its not the only muscle building androgen.
For example, several human and animals studies show that androstenedione and androstenediol actually have some fairly potent muscle building effects (52,53). Most interesting is that these studies showed that testosterone was not the active androgen causing these effects. The androgen supplementation caused only a moderate increases in testosterone -- yet the animals and humans were gaining muscle and losing body fat as if they had super-high testosterone levels. (52,53)
The explanation?
The androstenedione and androstenediol where building muscle themselves, proving that other androgens besides just testosterone, can be potent muscle building agents.
This fact is also supported by test-tube studies showing that these androgens bind to the androgen receptor in muscle tissue and directly initiate muscle growth. (46-52)
However, we still compare our AndroSeries products to testosterone just for simplicities sake. To read more about the "testosterone equivalent" of AndroSeries products visit this article - Whats new with AndroSeries v3?
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Figure 1
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Need Diet and Training Suggestions?
Get Your FREE Handbook
Every AndroSeries product contains its own Ultimate Results handbook.*
The handbook Includes -
1. Diet tips - Helpful suggestions on the type of foods to eat for the best results.
2. Training tips - Workout designed for the best results depending on the product. Provides a "recommended workout" including exercises, sets and reps.
3. Dosing and cycling tips - Provides info on getting the best results, proper post cycle therapy (PCT), and how to avoid side-effects.
High stearic shea nut oil, glyceryl monolinoleate/oleate, high linoleic safflower seed oil, phospholipid complex [standardized tp 35% phosphatidylcholine], ethoxylated sorbitan monooleate,Hormone Protection Complex™(Grapefruit peel oil, naringenin and quercetin extract) and medium chain triclycerides.
*Daily Value not established
Other Ingredients:
Kosher gelatin, tocopheryl acetate, glycerin, purified water, titanium dioxide, grape spirits, FD&C Blue #1, FD&C Blue #1 Alum. Lake, and FD&C Red #40 Alum. Lake.
† May be derived from soy
Recommended Use:
As a dietary supplement take 3-6 softgels upon rising, once daily. Take with or without meals. Do not exceed 6 softgels in a 24h period.
Do not use this product longer than 8 weeks without taking 8 weeks off between each cycle. 8 week off-time must exclude all steroidal products.
This product may be stacked with other AndroSeries™ products. For stacking recommendations, scan the QR code and see AndroStat, or visit www.androseries.info/androstat. Do not exceed 12 softgels total in a 24h period.
WARNING:
This product is not recommended for women, the elderly, anyone under the age of 21 or anyone diagnosed with a serious health condition including but not limited to cancer, BPH, epilepsy, depression, diabetes, cardiovascular disease or high blood pressure. Temporary side effects of this product may include weight gain, mildly reduced fertility, irritability, and oily skin.
Warning – Drug Interaction: A full serving (6 softgels) of this product contains the equivalent drug interaction effect of ~8fl. oz (240mL) of grapefruit juice which can significantly increase absorption of certain prescription drugs causing severe side-effects from overdose. A single dose of this product may influence the absorption of drugs for up to 24 hours. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. For more information, scan the QR code, or visit www.androseries.info/druginteractions.
Warning - Contains Steroids: Using this product may result in a positive test for steroids in organizations testing for performance enhancing compounds. This includes, IOC, NCAA, WADA, NFL, MLB, and other various sports and government agencies. This does NOT include typical pre-employment drug screening.
NOTICE:
This product is not intended to diagnose, treat, cure, or prevent any disease. Shipping Not Available to: Canada, Sweden, Singapore, Germany, or Australia.
(168 softgels)
%
More Information
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related discussion
Supplement Facts
Serving Size: 3 softgels
Servings per container:56
Amount Per Serving
%Daily Value
Super-4-DHEA™
(3-beta-enanthoxyandrost-4-en-17-one)
300mg*
-
Super-19-DHEA™
(3-beta-enanthoyloxynorandrost-4-en-17-one)
102mg*
-
Liqua-Vade Hormone Transport Complex™
2858mg*
-
High stearic shea nut oil, glyceryl monolinoleate/oleate, high linoleic safflower seed oil, phospholipid complex [standardized tp 35% phosphatidylcholine], ethoxylated sorbitan monooleate,Hormone Protection Complex™(Grapefruit peel oil, naringenin and quercetin extract) and medium chain triclycerides.
*Daily Value not established
Other Ingredients:
Kosher gelatin, tocopheryl acetate, glycerin, purified water, titanium dioxide, grape spirits, FD&C Blue #1, FD&C Blue #1 Alum. Lake, and FD&C Red #40 Alum. Lake.
† May be derived from soy
Recommended Use:
As a dietary supplement take 3-6 softgels upon rising, once daily. Take with or without meals. Do not exceed 6 softgels in a 24h period.
Do not use this product longer than 8 weeks without taking 8 weeks off between each cycle. 8 week off-time must exclude all steroidal products.
This product may be stacked with other AndroSeries™ products. For stacking recommendations, scan the QR code and see AndroStat, or visit www.androseries.info/androstat. Do not exceed 12 softgels total in a 24h period.
WARNING:
This product is not recommended for women, the elderly, anyone under the age of 21 or anyone diagnosed with a serious health condition including but not limited to cancer, BPH, epilepsy, depression, diabetes, cardiovascular disease or high blood pressure. Temporary side effects of this product may include weight gain, mildly reduced fertility, irritability, and oily skin.
Warning – Drug Interaction: A full serving (6 softgels) of this product contains the equivalent drug interaction effect of ~8fl. oz (240mL) of grapefruit juice which can significantly increase absorption of certain prescription drugs causing severe side-effects from overdose. A single dose of this product may influence the absorption of drugs for up to 24 hours. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. Dosing of prescribed medication may need to be adjusted if used concurrently with this product. For more information, scan the QR code, or visit www.androseries.info/druginteractions.
Warning - Contains Steroids: Using this product may result in a positive test for steroids in organizations testing for performance enhancing compounds. This includes, IOC, NCAA, WADA, NFL, MLB, and other various sports and government agencies. This does NOT include typical pre-employment drug screening.
NOTICE:
This product is not intended to diagnose, treat, cure, or prevent any disease. Shipping Not Available to: Canada, Sweden, Singapore, Germany, or Australia.
