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DERMACRINE
  • DHEA & Pregnenolone skin cream
  • Resveratrol & 7,8-Benzoflavone prevent estrogenic side effects
  • Enhances athletic performance, recovery and strength
  • Increases GH & IGF-1 to support muscle growth and fat reduction
  • Pregnenolone provides hair-loss protection


For information about the active ingredients in Dermacrine, please visit the Dermacrine Liqua-Vade page.

1. Administer lotion every morning, after a shower
2. Administer 4-5 pumps and apply to the skin*
3. Allow 4-5 minutes to dry

*Apply to shoulders and upper-back for best conversion

 

Only apply the product to clean, dry skin. Shaving off body hair is recommended, but not required. Also, avoid swimming, bathing or tanning for at least 6 hours after application.

How To Use Dermacrine

Dermacrine Muscle Stack

                   $179.95             

 

1. Sex Steroid Metabolism in Human Peripheral Blood Mononuclear Cells Changes with Aging 

The Journal of Clinical Endocrinology & Metabolism 90(11):6283-6289 (2005)

2. Conversion of dehydroepiandrosterone to downstream steroid hormones in macrophages. 
Schmidt M, et al.
J Endocrinol. 2000 Feb;164(2):161-9.

3. High bioavailability of dehydroepiandrosterone administered percutaneously in the rat 
C Labrie, et al. 
Sep 1996; 150: S107 - S118.

4. Effects of transdermal application of DHEA to men on the levels of steroids, gonadotropins and lipids. 
SULCOVÃ J, et al.
Physiol Res 49: 685-693, 2000.

5. Transformation in vitro of [4-14C ] dehydroepiandrosterone into 7-oxygenated derivatives by the normal human male and female skin tissue. 
Faredin, I., et al.
J. Invest. Dermatol. 52:357. 1969

6. The metabolism of [4-14C] 5 androstene-3P, 17P-diol by normal human skin in vitro. 
Faredin, et al. 
Acta Med. Acad. Sci. Hung. 32:139. 1975.

7. Sebocytes are the key regulators of androgen homeostasis in human skin. 
M Fritsch, et al.
J Invest Dermatol, May 1, 2001; 116(5): 793-800.

8. Transformation and conjugation of dehydroepiandrosterone by human skin. 
Berliner, D. L., et al. 
J. Clin. Endocrinol. 27:1214. 1967.

9. The formation of water soluble steroids by human skin. 
Berliner, D. L., et al.
J. Invest. Dermatol. 50:220. 1968

10. The in vitro metabolism of dehydroepiandrosterone in human skin. 
I Faredin, et al. 
Acta Med Acad Sci Hung, Jan 1967; 23(2): 169-79.

11. The metabolism of [4-14C] dehydroepiandrosterone by human skin in vitro. I. Transformation in vitro of [4-14C] dehydroepiandrosterone into Androst-4-ene-3,17-dione, testosterone and androsterone by normal human male and female skin slices. 
I Faredin, et al. 
Acta Med Acad Sci Hung, Jan 1970; 27(1): 95-102.

12. Ergosteroids: Induction of Thermogenic Enzymes in Liver of Rats Treated with Steroids Derived from Dehydroepiandrosterone.
H Lardy, et al. 
PNAS, Jul 1995; 92: 6617

13. Ergosteroids VI. Metabolism of dehydroepiandrosterone by rat liver in vitro: A liquid chromatographic mass spectrometric study.
Marwah, A., et al. 
J. Chromatog. (2002). B 767, 285-299.

14. Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone.
LARDY H, et al. 
Proc Natl Acad Sci USA 92: 6617-6619, 1995.

15. A randomized, double blind, placebo controlled study of 3 - acetyl - 7 - oxo - dehydroepiandrosterone in healthy overweight adults. 
Kalman, D., et al. 
(2000). Curr. Ther. Res. 61, 435-442.

16. The effect of 7 - keto Naturalean on weight loss: A randomized, double blind placebo controlled trial. Zenk, J., et al. 
(2002). Curr. Ther. Res. 63, 263-272.

17. How short-term transdermal treatment of men with 7-oxo-dehydroepiandrosterone influence thyroid function.
R Hampl, et al. 
Physiol Res, Jan 2006; 55(1): 49-54.

18. DHEA treatment for HIVþ patients: Effects on mood, androgenic and anabolic parameters. 
Rabkin, J., et al. 
Psychoneuro endocrinology. R. 25, 53-68. 2000

19. Activation of immune function by dehydroepiandrosterone (DHEA) in age- advanced men. 
Khorram O, et al.
J Gerontol 1997; 52A:M1- M7.

20. Oral dehydroepiandrosterone in physiologic doses modulates immune function in postmenopausal women. 
Casson PR, et al. 
Am J Obstet Gynecol. 169:1536-1539. 1993

21. Novel brain function: biosynthesis and actions of neurosteroids in neurons. 
K Tsutsui, et al. 
Neurosci Res, Apr 2000; 36(4): 261-73.

22. Individual differences in cognitive aging: implication of pregnenolone sulfate. 
W Mayo, et a. 
Prog Neurobiol, September 1, 2003; 71(1): 43-8.

23. Memory-Enhancing Effects in Male Mice of Pregnenolone and Steroids Metabolically Derived from it. 
JF Flood, et a. 
PNAS, Mar 1992; 89: 1567.

24. Steroid 5alpha-reductase inhibitors.
E Flores, et al.
Mini Rev Med Chem, May 1, 2003; 3(3): 225-37

25. Die Bedeutung der Passionsblume in der Heilkunde. 
Lutomski J et al.
Pharmazie in unserer Zeit 1981;10:45-49.

26. The Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies.
Tyler VE et al.
Pharmaceutical Products Press, New York, 1993.

27. Drug/substance reversal effects of a novel trisubstituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. -a brief perspective
KAMALDEEP DHAWAN et al.
Addiction Biology (December 2003) 8, 379 - 386

28. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
K Dhawan and et al. 
Life Sci, Nov 2002; 71(26): 3059-69.

29. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.
Kao YC, et al.
Environ Health Perspect 1998;106:85-92

30. Inhibition of human estrogen synthetase (aromatase) by flavones
JT Kellis, Jr et al.
Science, Sep 1984; 225: 1032 - 1034.

31. The Red Wine Polyphenol Resveratrol Displays Bilevel Inhibition on Aromatase in Breast Cancer Cells
Yun Wang, et al.
Toxicol. Sci., Jul 2006; 92: 71 - 77.

32. trans-Resveratrol, a Natural Antioxidant from Grapes, Increases Sperm Output in Healthy Rats M. Emà lia Juan, et al.
J. Nutr., Apr 2005; 135: 757 - 760

33. trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
S Shin, et al.
Arch Pharm Res, Jan 2008; 31(1): 83-7.

34. An open- label dose- escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease. 
Dyner TS, et al
J Acquir Immune Deficiency Syndrom 1993;6:459- 465.

35. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. Morales AJ, et al.
J Clin Endocrinol Me tab 1994;78:1360- 1367.

36. DHEA attenuates catecholamine secretion from bovine adrenal chromaffin cells. 
PS Liu et a. 
J Biomed Sci, Mar 2004; 11(2): 200-5.

37. DHEA administration increases rapid eye movement sleep and EEG power in the sigma frequency range.
Friess E, et al. 
Am J Physiol 1995;268:E107-E113.

38. Anticortisols: Their Potential Usefulness.
Baulieu, et al., 
Las Vegas , NV : Conference on Cortisol and Anti-Cortisols, 1997

39. Androstenediol reduces the anti-inflammatory effects of restraint stress during wound healing. 
CC Head, et al. 
Brain Behav Immun, Nov 2006; 20(6): 590-6.

40. Androstenetriol improves survival in a rodent model of traumatic shock. 
AC Marcu, et al. 
Resuscitation, December 1, 2006; 71(3): 379-86.

Dermacrine
(7.2 fl. oz. bottle)
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Price: $49.95

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Product Facts

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More Information

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Product Facts
Application Size: 5 pumps
Applications per container: 23

DHEA 
72mg**  
 


7,8-Benzoflavone (99%) 
36mg**  
 


Resveratrol (99%) 
36mg**  
 


Pregnenolone 
18mg**  
 


Chrysin (99%) 
9mg** 
 



Other Ingredients:

Distilled water, grape spirits*, aloe vera*, ethoxy diglycol, dimethyl isosorbide, butylene glycol, jojoba oil, emu oil, squalene, tocopherol acetate, chamomile extract* (matricaria recutita), isopropyl myristate, green tea extract* (camellia sinensis), cetyl palmitate, sorbitan palmitate, sorbitan olivate, glyceryl stearate, PEG 100 stearate, glycerin, dimethicone, strontium nitrate, hydroxypropyl methylcellulose, d-Limonene, tetrahydropiperine†, potassium sorbate, sodium benzoate, sodium PCA, sodium hydroxide.

* Certified Organic

† US Patent 6,849,645


WARNING:

Product may transfer to others by direct skin contact. Avoid direct skin contact with new born children. Product is not recommended for women, elderly, anyone under the age of 18 or anyone diagnosed with a serious health condition including but not limited to cancer, BPH, epilepsy, depression, diabetes, cardiovascular disease or high blood pressure. Always consult your physician before using this product with any over-the-counter or prescription medication.

NOTICE:

Fast drying creamy lotion, possessing fresh citrus scent.

This product is not intended to diagnose, treat, cure, or prevent any disease.








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