1. Sex Steroid Metabolism in Human Peripheral Blood Mononuclear Cells Changes with Aging
The Journal of Clinical Endocrinology & Metabolism 90(11):6283-6289 (2005)
2. Conversion of dehydroepiandrosterone to downstream steroid hormones in macrophages.
Schmidt M, et al.
J Endocrinol. 2000 Feb;164(2):161-9.
3. High bioavailability of dehydroepiandrosterone administered percutaneously in the rat
C Labrie, et al.
Sep 1996; 150: S107 - S118.
4. Effects of transdermal application of DHEA to men on the levels of steroids, gonadotropins and lipids.
SULCOVÃ J, et al.
Physiol Res 49: 685-693, 2000.
5. Transformation in vitro of [4-14C ] dehydroepiandrosterone into 7-oxygenated derivatives by the normal human male and female skin tissue.
Faredin, I., et al.
J. Invest. Dermatol. 52:357. 1969
6. The metabolism of [4-14C] 5 androstene-3P, 17P-diol by normal human skin in vitro.
Faredin, et al.
Acta Med. Acad. Sci. Hung. 32:139. 1975.
7. Sebocytes are the key regulators of androgen homeostasis in human skin.
M Fritsch, et al.
J Invest Dermatol, May 1, 2001; 116(5): 793-800.
8. Transformation and conjugation of dehydroepiandrosterone by human skin.
Berliner, D. L., et al.
J. Clin. Endocrinol. 27:1214. 1967.
9. The formation of water soluble steroids by human skin.
Berliner, D. L., et al.
J. Invest. Dermatol. 50:220. 1968
10. The in vitro metabolism of dehydroepiandrosterone in human skin.
I Faredin, et al.
Acta Med Acad Sci Hung, Jan 1967; 23(2): 169-79.
11. The metabolism of [4-14C] dehydroepiandrosterone by human skin in vitro. I. Transformation in vitro of [4-14C] dehydroepiandrosterone into Androst-4-ene-3,17-dione, testosterone and androsterone by normal human male and female skin slices.
I Faredin, et al.
Acta Med Acad Sci Hung, Jan 1970; 27(1): 95-102.
12. Ergosteroids: Induction of Thermogenic Enzymes in Liver of Rats Treated with Steroids Derived from Dehydroepiandrosterone.
H Lardy, et al.
PNAS, Jul 1995; 92: 6617
13. Ergosteroids VI. Metabolism of dehydroepiandrosterone by rat liver in vitro: A liquid chromatographic mass spectrometric study.
Marwah, A., et al.
J. Chromatog. (2002). B 767, 285-299.
14. Ergosteroids: induction of thermogenic enzymes in liver of rats treated with steroids derived from dehydroepiandrosterone.
LARDY H, et al.
Proc Natl Acad Sci USA 92: 6617-6619, 1995.
15. A randomized, double blind, placebo controlled study of 3 - acetyl - 7 - oxo - dehydroepiandrosterone in healthy overweight adults.
Kalman, D., et al.
(2000). Curr. Ther. Res. 61, 435-442.
16. The effect of 7 - keto Naturalean on weight loss: A randomized, double blind placebo controlled trial. Zenk, J., et al.
(2002). Curr. Ther. Res. 63, 263-272.
17. How short-term transdermal treatment of men with 7-oxo-dehydroepiandrosterone influence thyroid function.
R Hampl, et al.
Physiol Res, Jan 2006; 55(1): 49-54.
18. DHEA treatment for HIVþ patients: Effects on mood, androgenic and anabolic parameters.
Rabkin, J., et al.
Psychoneuro endocrinology. R. 25, 53-68. 2000
19. Activation of immune function by dehydroepiandrosterone (DHEA) in age- advanced men.
Khorram O, et al.
J Gerontol 1997; 52A:M1- M7.
20. Oral dehydroepiandrosterone in physiologic doses modulates immune function in postmenopausal women.
Casson PR, et al.
Am J Obstet Gynecol. 169:1536-1539. 1993
21. Novel brain function: biosynthesis and actions of neurosteroids in neurons.
K Tsutsui, et al.
Neurosci Res, Apr 2000; 36(4): 261-73.
22. Individual differences in cognitive aging: implication of pregnenolone sulfate.
W Mayo, et a.
Prog Neurobiol, September 1, 2003; 71(1): 43-8.
23. Memory-Enhancing Effects in Male Mice of Pregnenolone and Steroids Metabolically Derived from it.
JF Flood, et a.
PNAS, Mar 1992; 89: 1567.
24. Steroid 5alpha-reductase inhibitors.
E Flores, et al.
Mini Rev Med Chem, May 1, 2003; 3(3): 225-37
25. Die Bedeutung der Passionsblume in der Heilkunde.
Lutomski J et al.
Pharmazie in unserer Zeit 1981;10:45-49.
26. The Honest Herbal: A Sensible Guide to the Use of Herbs and Related Remedies.
Tyler VE et al.
Pharmaceutical Products Press, New York, 1993.
27. Drug/substance reversal effects of a novel trisubstituted benzoflavone moiety (BZF) isolated from Passiflora incarnata Linn. -a brief perspective
KAMALDEEP DHAWAN et al.
Addiction Biology (December 2003) 8, 379 - 386
28. Prevention of chronic alcohol and nicotine-induced azospermia, sterility and decreased libido, by a novel tri-substituted benzoflavone moiety from Passiflora incarnata Linneaus in healthy male rats.
K Dhawan and et al.
Life Sci, Nov 2002; 71(26): 3059-69.
29. Molecular basis of the inhibition of human aromatase (estrogen synthetase) by flavone and isoflavone phytoestrogens: A site-directed mutagenesis study.
Kao YC, et al.
Environ Health Perspect 1998;106:85-92
30. Inhibition of human estrogen synthetase (aromatase) by flavones
JT Kellis, Jr et al.
Science, Sep 1984; 225: 1032 - 1034.
31. The Red Wine Polyphenol Resveratrol Displays Bilevel Inhibition on Aromatase in Breast Cancer Cells
Yun Wang, et al.
Toxicol. Sci., Jul 2006; 92: 71 - 77.
32. trans-Resveratrol, a Natural Antioxidant from Grapes, Increases Sperm Output in Healthy Rats M. Emà lia Juan, et al.
J. Nutr., Apr 2005; 135: 757 - 760
33. trans-Resveratrol relaxes the corpus cavernosum ex vivo and enhances testosterone levels and sperm quality in vivo.
S Shin, et al.
Arch Pharm Res, Jan 2008; 31(1): 83-7.
34. An open- label dose- escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease.
Dyner TS, et al
J Acquir Immune Deficiency Syndrom 1993;6:459- 465.
35. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. Morales AJ, et al.
J Clin Endocrinol Me tab 1994;78:1360- 1367.
36. DHEA attenuates catecholamine secretion from bovine adrenal chromaffin cells.
PS Liu et a.
J Biomed Sci, Mar 2004; 11(2): 200-5.
37. DHEA administration increases rapid eye movement sleep and EEG power in the sigma frequency range.
Friess E, et al.
Am J Physiol 1995;268:E107-E113.
38. Anticortisols: Their Potential Usefulness.
Baulieu, et al.,
Las Vegas , NV : Conference on Cortisol and Anti-Cortisols, 1997
39. Androstenediol reduces the anti-inflammatory effects of restraint stress during wound healing.
CC Head, et al.
Brain Behav Immun, Nov 2006; 20(6): 590-6.
40. Androstenetriol improves survival in a rodent model of traumatic shock.
AC Marcu, et al.
Resuscitation, December 1, 2006; 71(3): 379-86.